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. 2014 Dec;49(14):1920-7.
doi: 10.3109/10826084.2014.935793. Epub 2014 Aug 6.

A signal detection analysis of executive control performance among adolescent inhalant and cannabis users

Affiliations

A signal detection analysis of executive control performance among adolescent inhalant and cannabis users

Michael J Takagi et al. Subst Use Misuse. 2014 Dec.

Abstract

Background: Inhalant users have multiple comorbid issues (e.g., polydrug use) that complicate identifying inhalant-specific cognitive deficits.

Objectives: The aim of the present study was to use signal detection theory to identify inhalant-specific differences in executive control.

Methods: We examined three well-matched groups: 19 inhalant users, 19 cannabis users, and 19 controls using Stroop and Go/No-Go tasks.

Results: Inhalant users demonstrated significantly lower d-prime scores relative to controls, but not cannabis users, on both tasks, suggesting possible executive deficits relative to controls. CONCLUSIONS/IMPORTANCE: The results of this study raise questions regarding inhalant toxicity and the vulnerability of the adolescent brain to drugs of abuse.

Keywords: Go/No-Go; Stroop; cannabis; cognitive control; d-prime; inhalants; signal detection.

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