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Comment
. 2014 Aug 5;20(2):203-5.
doi: 10.1016/j.cmet.2014.07.019.

Another Shp on the horizon for bile acids

Alessia Perino  1 , Kristina Schoonjans  2
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Free article
Comment

Another Shp on the horizon for bile acids

Alessia Perino et al. Cell Metab. .
Free article

Abstract

Bile acid metabolism is tightly controlled due to the toxic effects of bile acid overload. In this issue, research from the Feng lab reports Shp2 as a novel integrator of hepatic bile acid and FGF15/FGF19 signaling, adding another layer of complexity to the control of bile acid biosynthesis.

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