Zylka et al. reply

Affiliations

¹ 1] Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA [2] Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA [3] UNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
² Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

Comment

Mark J Zylka et al. Nature. 2014.

. 2014 Aug 7;512(7512):E2.

doi: 10.1038/nature13584.

¹ 1] Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA [2] Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA [3] UNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
² Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

No abstract available

Comment on

Topoisomerases facilitate transcription of long genes linked to autism.
King IF, Yandava CN, Mabb AM, Hsiao JS, Huang HS, Pearson BL, Calabrese JM, Starmer J, Parker JS, Magnuson T, Chamberlain SJ, Philpot BD, Zylka MJ. King IF, et al. Nature. 2013 Sep 5;501(7465):58-62. doi: 10.1038/nature12504. Epub 2013 Aug 28. Nature. 2013. PMID: 23995680 Free PMC article.
Bias towards large genes in autism.
Shohat S, Shifman S. Shohat S, et al. Nature. 2014 Aug 7;512(7512):E1-2. doi: 10.1038/nature13583. Nature. 2014. PMID: 25100484 No abstract available.

1. Solier S, et al. Transcription Poisoning by Topoisomerase I Is Controlled by Gene Length, Splice Sites, and miR-142-3p. Cancer Res. 2013;73:4830–4839. - PMC - PubMed
1. Teves SS, Henikoff S. Transcription-generated torsional stress destabilizes nucleosomes. Nat. Struct. Mol. Biol. 2014;21:88–94. - PMC - PubMed
1. Veloso A, et al. Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin. PLoS ONE. 2013;8:e78190. - PMC - PubMed
1. Abrahams BS, et al. SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs) Mol. Autism. 2013;4:36. - PMC - PubMed
1. Vaags AK, et al. Rare Deletions at the Neurexin 3 Locus in Autism Spectrum Disorder. Am. J. Hum. Genet. 2012;90:133–141. - PMC - PubMed