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Randomized Controlled Trial
. 2014 Aug 7;11(8):7961-76.
doi: 10.3390/ijerph110807961.

Effectiveness of a new exercise program after lower limb arterial blood flow surgery in patients with peripheral arterial disease: a randomized clinical trial

Edita Jakubsevičienė  1 , Donatas Vasiliauskas  2 , Linas Velička  3 , Raimondas Kubilius  4 , Eglė Milinavičienė  5 , Jonė Venclovienė  6
Affiliations
Randomized Controlled Trial

Effectiveness of a new exercise program after lower limb arterial blood flow surgery in patients with peripheral arterial disease: a randomized clinical trial

Edita Jakubsevičienė et al. Int J Environ Res Public Health. .

Abstract

Objective: The aim of this study was to evaluate the effectiveness of a supervised exercise program (SEP) plus at home nonsupervised exercise therapy (non-SET) on functional status, quality of life (QoL) and hemodynamic response in post-lower-limb bypass surgery patients.

Results: One hundred and seventeen patients were randomized to an intervention (n = 57) or a control group (n = 60). A new individual SEP was designed for patients with peripheral arterial disease (PAD) and applied to the studied subjects of the intervention group who also continued non-SET at home, whereas those assigned to the control group received just usual SEP according to a common cardiovascular program. The participants of the study were assessed by a 6-min walking test (6 MWT), an ankle-brachial index (ABI), and the Medical Outcomes Study Short Form-36 (SF-36) of QoL at baseline, at 1 and 6 months after surgery. A significant improvement was observed in the walked distance in the intervention group after 6 months compared with the control group (p < 0.001). The intervention group had significantly higher QoL score in the physical and mental component of SF-36 (p < 0.05).

Conclusions: A 6-month application of the new SEP and non-SET at home has yielded significantly better results in walking distance and QoL in the intervention group than in the controls.

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Figures

Figure 1
Figure 1
CONSORT flow chart of the study.
Figure 2
Figure 2
The total six-min walk test measurements at baseline, at 1 and 6 months after the surgery in the intervention (n = 57) and control groups (n = 60).
Figure 3
Figure 3
Pain-free walking distance measurements during six-min walk test at baseline, at 1 and 6 months after the surgery in the intervention (n = 57) and control groups (n = 60).
Figure 4
Figure 4
Peripheral hemodynamic measurements at baseline, at 1 and 6 months after the surgery in the intervention (n = 57) and control groups (n = 60). ABI = ankle-brachial index; error bars indicate ± standard error; months = after bypass surgery.
See this image and copyright information in PMC

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