Leptin receptor makes its mark on MSCs
- PMID: 25105573
- DOI: 10.1016/j.stem.2014.07.001
Leptin receptor makes its mark on MSCs
Abstract
Although mesenchymal stem/stromal cells (MSCs) are an important component of the hematopoietic niche, the markers that correlate with their physiological functions have not been defined. In this issue of Cell Stem Cell, Zhou et al. (2014) identify the Leptin Receptor as a marker for prospective identification and in vivo fate mapping of bone marrow MSCs.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.Cell Stem Cell. 2014 Aug 7;15(2):154-68. doi: 10.1016/j.stem.2014.06.008. Epub 2014 Jun 19. Cell Stem Cell. 2014. PMID: 24953181 Free PMC article.
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