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Review
. 2014 Oct;21(5):372-6.
doi: 10.1097/MED.0000000000000090.

Environmental perchlorate exposure: potential adverse thyroid effects

Angela M Leung  1 , Elizabeth N Pearce, Lewis E Braverman
Affiliations
Review

Environmental perchlorate exposure: potential adverse thyroid effects

Angela M Leung et al. Curr Opin Endocrinol Diabetes Obes. 2014 Oct.

Abstract

Purpose of review: This review will present a general overview of the sources, human studies, and proposed regulatory action regarding environmental perchlorate exposure.

Recent findings: Some recent studies have reported significant associations between urinary perchlorate concentrations, thyroid dysfunction, and decreased infant intelligence quotient in groups who would be particularly susceptible to perchlorate effects. An update regarding the recently proposed regulatory actions and potential costs surrounding amelioration of perchlorate contamination is provided.

Summary: The potential adverse thyroidal effects of environmental perchlorate exposure remain controversial, and further research is needed to further define its relationship to human health among pregnant and lactating women and their infants.

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References

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