Alteplase in acute ischaemic stroke: the need for speed

Affiliations

¹ Department of Clinical Neuroscience, University of Calgary, Calgary, AB T2N 2T9, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Medicine, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Radiology, University of Calgary, Calgary, AB T2N 2T9, Canada. Electronic address: michael.hill@ucalgary.ca.
² Department of Clinical Neuroscience, University of Calgary, Calgary, AB T2N 2T9, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 2T9, Canada.

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Michael D Hill et al. Lancet. 2014.

Free article

. 2014 Nov 29;384(9958):1904-6.

doi: 10.1016/S0140-6736(14)60662-0. Epub 2014 Aug 5.

¹ Department of Clinical Neuroscience, University of Calgary, Calgary, AB T2N 2T9, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Medicine, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Radiology, University of Calgary, Calgary, AB T2N 2T9, Canada. Electronic address: michael.hill@ucalgary.ca.
² Department of Clinical Neuroscience, University of Calgary, Calgary, AB T2N 2T9, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 2T9, Canada.

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Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.
Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, Lansberg M, Lindley RI, Murray G, Olivot JM, Parsons M, Tilley B, Toni D, Toyoda K, Wahlgren N, Wardlaw J, Whiteley W, del Zoppo GJ, Baigent C, Sandercock P, Hacke W; Stroke Thrombolysis Trialists' Collaborative Group. Emberson J, et al. Lancet. 2014 Nov 29;384(9958):1929-35. doi: 10.1016/S0140-6736(14)60584-5. Epub 2014 Aug 5. Lancet. 2014. PMID: 25106063 Free PMC article. Review.