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. 2014 Dec:30:27-9.
doi: 10.1016/j.anaerobe.2014.07.010. Epub 2014 Aug 7.

Corticosteroid use is associated with a reduced incidence of Clostridium difficile-associated diarrhea: a retrospective cohort study

Amy L Wojciechowski  1 , Ganapathi I Parameswaran  2 , Arun Mattappallil  3 , Kari A Mergenhagen  4
Affiliations

Corticosteroid use is associated with a reduced incidence of Clostridium difficile-associated diarrhea: a retrospective cohort study

Amy L Wojciechowski et al. Anaerobe. 2014 Dec.

Abstract

The impact of corticosteroid use on the incidence of Clostridium difficile-associated diarrhea (CDAD) was examined retrospectively in 532 patients receiving antibiotic treatment for respiratory infections. As determined by logistic regression, corticosteroids were associated with a decreased incidence of CDAD (Odds Ratio 0.12, 95% Confidence Interval 0.006-0.95).

Keywords: Clostridium difficile; Enterocolitis; Glucocorticoids; Prevention & control; Pseudomembranous.

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