Fifteen minute consultation: managing neonatal and childhood herpes encephalitis
- PMID: 25112286
- PMCID: PMC4392236
- DOI: 10.1136/archdischild-2014-306321
Fifteen minute consultation: managing neonatal and childhood herpes encephalitis
Abstract
Herpes simplex encephalitis (HSE) is the most common single cause of viral encephalitis in infants and children. Treated or untreated, it can be associated with considerable morbidity and mortality, and its presentation is usually insidious and non-specific. Prompt and careful investigation is important in order to establish the diagnosis so that treatment can be optimised. We address some common questions arising when diagnosing and treating presumed HSE throughout childhood.
Keywords: Evidence Based Medicine; Immunology; Infectious Diseases; Neonatology; Neurology.
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References
-
- Whitley RJ, Kimberlin DW. Herpes simplex encephalitis: children and adolescents. Sem Pediatr Infect Dis 2005;16:17–23. - PubMed
-
- Jurado R, Walker HK. Cerebrospinal fluid. In: Walker HK, Hall WD, Hurst JW, eds. Clinical methods: the history, physical, and laboratory examinations. 3rd edn Boston: Butterworths, 1990. Chapter 5, there are no page numbers as this is an online book. - PubMed
-
- Long SS, Pool TE, Vodzak J, et al. Herpes simplex virus infection in young infants during 2 decades of empiric acyclovir therapy. Pediatr Infect Dis J 2011;30:556–61. - PubMed
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