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. 2014 Jun;5(2):142-3.
doi: 10.1007/s13193-014-0304-9. Epub 2014 Mar 29.

Intussusception of a small bowel large B-cell lymphoma

William C Palmer  1 , Ron G Landmann  1 , Dustin L Eck  1 , David M Menke  1 , John R Cangemi  1
Affiliations

Intussusception of a small bowel large B-cell lymphoma

William C Palmer et al. Indian J Surg Oncol. 2014 Jun.

Abstract

Gastrointestinal tumors can rarely cause intestinal intussusception. Herein, we describe a 74 year-old male with a presumed diagnosis of Crohn's disease who presented with persistent symptoms refractory to medical management. Radiography demonstrated small bowel intussusception into the cecum. Lower endoscopy with biopsy diagnosed small bowel large Bcell lymphoma. Management included laparoscopic ileocecectomy and adjuvant R-CHOP chemotherapy. Long term outcomes of small bowel large B-cell lymphoma are related to disease stage at diagnosis, and average close to 75 %.

Keywords: Gastrointestinal tumors; Intussusception; Large B-cell lymphoma; Small bowel malignancy.

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Figures

Fig. 1
Fig. 1
Coronal CT demonstrating intussusception. Note the invagination of the intussusceptum (terminal ileum, TI) into the intussuscipiens (cecum, C)
Fig. 2
Fig. 2
Endoscopic view of the lymphoma functioning as the intussusceptum through the ileocecal valve into the cecum
Fig. 3
Fig. 3
a Laparoscopic and b gross pathological view of the lymphoma (L) and intussusceptum (TI) invaginating into the intussuscipiens (cecum, C)
Fig. 4
Fig. 4
Hematoxylin and eosin staining at 100x showing diffuse large B cell lymphoma infiltrating small bowel villi
See this image and copyright information in PMC

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