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Comment
. 2014 Aug 11;30(3):251-2.
doi: 10.1016/j.devcel.2014.07.009.

A role for β3-integrins in linking breast development and cancer

Ahmet Ucar  1 , Charles H Streuli  2
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A role for β3-integrins in linking breast development and cancer

Ahmet Ucar et al. Dev Cell. .
Free article

Abstract

Pregnancy induces a rapid and controlled expansion of mammary stem cells. In this issue of Developmental Cell, Desgrosellier et al. (2014) show that β3-integrin is required downstream of hormonal signaling and TGFβ2 to regulate mammary stem cell number and alveolar development specifically during early pregnancy.

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