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Meta-Analysis
. 2014 Oct;208(4):605-18.
doi: 10.1016/j.amjsurg.2014.06.006. Epub 2014 Jul 18.

A meta-analysis of complications following deceased donor liver transplant

Lisa M McElroy  1 , Amna Daud  2 , Ashley E Davis  2 , Brittany Lapin  2 , Talia Baker  2 , Michael M Abecassis  2 , Josh Levitsky  2 , Jane L Holl  3 , Daniela P Ladner  4
Affiliations
Meta-Analysis

A meta-analysis of complications following deceased donor liver transplant

Lisa M McElroy et al. Am J Surg. 2014 Oct.

Abstract

Background: Liver transplantation is a complex surgery associated with high rates of postoperative complications. While national outcomes data are available, national rates of most complications are unknown.

Data sources: A systematic review of the literature reporting rates of postoperative complications between 2002 and 2012 was performed. A cohort of 29,227 deceased donor liver transplant recipients from 74 studies was used to calculate pooled incidences for 17 major postoperative complications.

Conclusions: This is the first comprehensive review of postoperative complications after liver transplantation and can serve as a guide for transplant and nontransplant clinicians. Efforts to collect national data on complications, such as through the National Surgical Quality Improvement Program, would improve the ability to provide patients with informed consent, serve as a tool for individual center performance monitoring, and provide a central source against which to measure interventions aimed at improving patient care.

Keywords: Liver transplantation; Patient outcomes; Postoperative complications; Secondary analysis.

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Figures

Figure 1
Figure 1. Literature search and exclusion schematic
Figure 2
Figure 2. Forest Plots of Quantitatively Analyzed Studies
Figure 2
Figure 2. Forest Plots of Quantitatively Analyzed Studies
Figure 2
Figure 2. Forest Plots of Quantitatively Analyzed Studies
Figure 2
Figure 2. Forest Plots of Quantitatively Analyzed Studies
Figure 2
Figure 2. Forest Plots of Quantitatively Analyzed Studies
See this image and copyright information in PMC

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