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Review
. 2014:2014:709152.
doi: 10.1155/2014/709152. Epub 2014 Jul 10.

Zinc therapy in dermatology: a review

Mrinal Gupta  1 , Vikram K Mahajan  1 , Karaninder S Mehta  1 , Pushpinder S Chauhan  1
Affiliations
Review

Zinc therapy in dermatology: a review

Mrinal Gupta et al. Dermatol Res Pract. 2014.

Abstract

Zinc, both in elemental or in its salt forms, has been used as a therapeutic modality for centuries. Topical preparations like zinc oxide, calamine, or zinc pyrithione have been in use as photoprotecting, soothing agents or as active ingredient of antidandruff shampoos. Its use has expanded manifold over the years for a number of dermatological conditions including infections (leishmaniasis, warts), inflammatory dermatoses (acne vulgaris, rosacea), pigmentary disorders (melasma), and neoplasias (basal cell carcinoma). Although the role of oral zinc is well-established in human zinc deficiency syndromes including acrodermatitis enteropathica, it is only in recent years that importance of zinc as a micronutrient essential for infant growth and development has been recognized. The paper reviews various dermatological uses of zinc.

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References

    1. Nitzan YB, Cohen AD. Zinc in skin pathology and care. Journal of Dermatological Treatment. 2006;17(4):205–210. - PubMed
    1. Kitamura H, Morikawa H, Kamon H, et al. Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function. Nature Immunology. 2006;7(9):971–977. - PubMed
    1. Brocard A, Knol A, Khammari A, Dréno B. Hidradenitis suppurativa and zinc: a new therapeutic approach—a pilot study. Dermatology. 2007;214(4):325–327. - PubMed
    1. Sharma NL. Zinc, an update. Indian Journal of Dermatology, Venereology and Leprology. 1985;51:305–308. - PubMed
    1. Bangash HK, Sethi A. Handbook of Diet, Nutrition and the Skin. Vol. 2. Wageningen Academic; 2012. Zinc and skin health: an overview; pp. 178–195. (Human Health Handbooks no. 1).