A Study of Etiological Pattern in an Epidemic of Acute Febrile Illness during Monsoon in a Tertiary Health Care Institute of Uttarakhand, India
- PMID: 25121013
- PMCID: PMC4129282
- DOI: 10.7860/JCDR/2014/8965.4435
A Study of Etiological Pattern in an Epidemic of Acute Febrile Illness during Monsoon in a Tertiary Health Care Institute of Uttarakhand, India
Abstract
Background: Many parts of India are endemic for the dengue, malaria, typhoid and scrub typhus infections. The relative contribution of these illnesses in an outbreak of acute febrile illness is not known in this region.
Objective: The present study was conducted to find out the etiological pattern in an epidemic of acute febrile illness in Uttarakhand during the monsoon period. The study also focuses on concurrent infections and tries to find out the mortality outcomes.
Materials and methods: A retrospective study of four months was conducted on 1141 patients who presented with fever, and were suspected to have dengue, malaria, typhoid or scrub typhus. Patients of 12-years of age or above were included in the study. Serological tests for dengue, malaria, typhoid and scrub typhus were performed. Slides for malaria parasite were examined. In case of enteric fever only culture positive cases were included in the study.
Result: Among the 1141 febrile patients dengue was detected in 812(71.2 %), malaria in 146(12.8%), typhoid in 92(8.1%) and scrub typhus in 69(6.0%) cases. Mixed infection was noted in 22(1.9%).
Conclusion: Maximum (71.2 %) cases of fever were caused by dengue but significant number (32.3%) of patients suffered from malaria typhoid and scrub typhus. Many (1.9%) suffered from concurrent and multiple infections.
Keywords: Dengue; Epidemic; Malaria; Scrub typhus Typhoid.
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References
-
- Anthony DR, Balsari S, Clark S, Straff DJ, Rajavelu P, Rajagopalan A. The EMcounter Project: A Study of the Epidemiology of Medical Emergencies in India. Ann Emerg Med. 2007;50:129–30.
-
- Chrispal A, Boorugu H, Gopinath KG, Chandy S, Prakash JA, Thomas EM, et al. Acute undifferentiated febrile illness in adult hospitalized patients: the disease spectrum and diagnostic predictors - an experience from a tertiary care hospital in South India. Trop Doct. 2010;40:230–4. - PubMed
-
- Yong LS, Koh KC. A Case of Mixed Infections in a Patient Presenting with Acute Febrile Illness in the Tropics. http://dx.doi.org/10.1155/2013/562175. - DOI - PMC - PubMed
-
- Tangkanakul W, Kingnate D. Leptospirosis epidemic in north–eastern provinces, 1997. Journal of Health Sciences. 1998;3:386–95.
-
- Brown GW, Shirai A, Jegathesan M, Burke DS, Twartz JC, Saunders JP, et al. Febrile illnesses in Malaysia: an analysis of 1,629 hospitalized patients. American Journal of Tropical Medicine and Hygiene. 1984;33:311–5. - PubMed
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