First do no harm: infectious deaths in pediatric ALL
- PMID: 25124779
- PMCID: PMC4133499
- DOI: 10.1182/blood-2014-06-581603
First do no harm: infectious deaths in pediatric ALL
Abstract
In this issue of Blood, O’Connor and colleagues describe infection-related mortality on the United Kingdom Childhood Acute Lymphoblastic Leukaemia Randomised Trial 2003 (UKALL 2003) for children with newly diagnosed acute lymphoblastic leukemia, reporting a 5-year cumulative incidence of 2.4%, with Down syndrome (DS) being the factor most predictive of increased risk.
Conflict of interest statement
Conflict-of-interest disclosure: The author declares no competing financial interests.
Figures
Comment on
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Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003.Blood. 2014 Aug 14;124(7):1056-61. doi: 10.1182/blood-2014-03-560847. Epub 2014 Jun 5. Blood. 2014. PMID: 24904116 Clinical Trial.
References
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- O’Connor D, Bate J, Wade R, et al. Infection-related mortality in children with acute lymphoblastic leukemia: a retrospective analysis of infectious deaths on UKALL 2003. Blood. 2014;124(7):1056–1061. - PubMed
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- Vora A, Goulden N, Wade R, et al. Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial. Lancet Oncol. 2013;14(3):199–209. - PubMed
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