Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Mar;3(2):117-22.

Evolving trends in insulin delivery in pursuit of improvements in diabetes management

Firas Akhrass  1 , Nancy Skinner  2 , Kimberly Boswell  3 , Luther B Travis  4
Affiliations

Evolving trends in insulin delivery in pursuit of improvements in diabetes management

Firas Akhrass et al. Am Health Drug Benefits. 2010 Mar.

Abstract

Diabetes mellitus affects 23.6 million Americans and its incidence is rapidly increasing, particularly in older, overweight patients. Large-scale studies conclusively show that elevated blood glucose levels are associated with an increased risk for microvascular complications, such as retinopathy and nephropathy. The high rates of morbidity and mortality associated with this disease, and the costs associated with it, underscore the importance of effective glycemic control. Conventional syringe/vial insulin delivery is associated with many barriers for patients with diabetes mellitus and for their healthcare providers. Substantial developments in insulin delivery show promise in overcoming these barriers. New technologies in insulin delivery focus on increasing patient convenience, reducing the frequency of daily injections, and improving glycemic control. This article outlines the challenges associated with conventional insulin delivery and describes recent developments that may help to overcome these barriers and, ultimately, could enhance glycemic control.

PubMed Disclaimer

Figures

None
Luther B. Travis
See this image and copyright information in PMC

References

    1. National Institute of Diabetes and Digestive and Kidney Diseases. National Diabetes Statistics, 2007. www.niddk.nih.gov/health/diabetes/pubs/dmstats/dmstats.htm#7. Accessed July 2, 2008.
    1. Carver C. Insulin treatment and the problem of weight gain in type 2 diabetes. Diabetes Educ. 2006; 32: 910–917. - PubMed
    1. Bakris GL, Williams M, Dworkin L, et al. Preserving renal function in adults with hypertension and diabetes: a consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Am J Kidney Dis. 2000; 36: 646–661. - PubMed
    1. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993; 329: 977–986. - PubMed
    1. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998; 352: 837–853 Erratum in: Lancet. 1999; 354: 602. - PubMed

LinkOut - more resources