Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep 5;16(17):4480-3.
doi: 10.1021/ol502027m. Epub 2014 Aug 15.

Enantioselective synthesis of the predominant AB ring system of the Schisandra nortriterpenoid natural products

Birgit Gockel  1 , Shermin S Goh, Emma J Puttock, Hannah Baars, Guilhem Chaubet, Edward A Anderson
Affiliations

Enantioselective synthesis of the predominant AB ring system of the Schisandra nortriterpenoid natural products

Birgit Gockel et al. Org Lett. .

Abstract

An enantioselective synthesis of the AB ring system common to the majority of the Schisandra nortriterpenoid natural products is reported. Key steps include a stereospecific ring opening of a trisubstituted epoxide and the use of a β-lactone to enable installation of the gem-dimethyl functionality of the B ring. An acetalization strategy played a key role in a late-stage biomimetic AB ring bicyclization.

PubMed Disclaimer

Publication types