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Review
. 2015 Jan 1;20(1):e1-6.
doi: 10.4317/medoral.19842.

Odontogenic myxofibroma: a concise review of the literature with emphasis on the surgical approach

Marco Meleti  1 , Ilaria Giovannacci, Domenico Corradi, Maddalena Manfredi, Elisabetta Merigo, Mauro Bonanini, Paolo Vescovi
Affiliations
Review

Odontogenic myxofibroma: a concise review of the literature with emphasis on the surgical approach

Marco Meleti et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Purpose: The aim of this work is to report a review of the literature concerning epidemiology, clinical and radiographic features as well as treatment of odontogenic myxofibroma (MF).

Methods: The PubMed database was searched using the following keywords: "odontogenic myxofibroma", "odontogenic fibromyxoma", "myxofibroma of the jaw" and "fibromyxoma of the jaw".

Results: Fifteen articles reporting the experience with 24 patients were identified. Male/female ratio was 1:1.4 and the average age 29.5 years. The most frequent location was the mandible. In 66.7% of the cases the radiographic appearance was a multilocular radiolucency. Swelling was observed in 13 patients (92.86%), varying degrees of pain in 5 (35.71%) and paresthesia in only one patient (7.14%). Six out of 24 patients (26.09%) were treated with radical surgery and 17 out of 24 (73.91%) with a conservative approach. In two out of 21 cases (9.52%) a recurrence was reported.

Conclusions: MF is an extremely rare tumour and no agreement exist on the causes of its development. According to the present review, the choice of treatment should depend on variables such as localization, presence of a primary or of a recurrent lesion, age, general medical conditions and aesthetic needs of the patient.

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Conflict of interest statement

Conflict of interest statement: The authors have declared that no conflict of interest exist.

Figures

Figure 1
Figure 1
Radiographic imaging – A) orthopantomography showing a radiolucent multilocular and multilobular lesion associated with impacted right third molar of the mandible. B) axial CT Scan showing the radiolucent lesion within intact buccal and cortical bone.
Figure 2
Figure 2
Surgical treatment – A) mucoperiosteal flap B) enucleation of the lesion C) residual cavity D) suture.
Figure 3
Figure 3
Histopathologic view of MF (H&E staining) – A) 20X magnification; B) 10X magnification.
See this image and copyright information in PMC

References

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