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Case Reports
. 2014 Aug 6;5(3):191-5.
doi: 10.4292/wjgpt.v5.i3.191.

Statins and their role in acute pancreatitis: Case report and literature review

Denzil Etienne  1 , Yousef Reda  1
Affiliations
Case Reports

Statins and their role in acute pancreatitis: Case report and literature review

Denzil Etienne et al. World J Gastrointest Pharmacol Ther. .

Abstract

Statin induced pancreatitis has historically been considered a diagnosis of exclusion, with literature references typically in the form of case reports and observational studies. Recently, larger studies have challenged the correlations made by earlier case reports, and instead demonstrate a mild protective effect in statin users. We present a case report of likely statin induced pancreatitis in a 58-year-old male (which we have attributed to drug-drug interaction with resulting inhibition of hepatic cytochrome P450 enzymes) and have reviewed the apparent dichotomy in the available literature.

Keywords: CYP450; Inflammation; Pancreatitis; Statin; Toxic.

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Figures

Figure 1
Figure 1
Cross-sectional view of computer tomography abdomen with contrast showing pancreatitis of the body and tail.
See this image and copyright information in PMC

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