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. 2014 Mar 1;1(1):48-57.
doi: 10.1007/s40521-013-0004-7.

Oral and sublingual immunotherapy

Edwin H Kim  1 , Wesley Burks  2
Affiliations

Oral and sublingual immunotherapy

Edwin H Kim et al. Curr Treat Options Allergy. .

Abstract

Allergic diseases have continued to increase throughout the developed world. Subcutaneous immunotherapy has been a mainstay of treatment for allergic rhinitis and asthma, however, some patients are precluded from treatment. On the other hand, in the case of food allergy, treatments simply do not exist. Oral and sublingual immunotherapy, with its superior safety and ease of administration, offers an alternative for patients with allergic rhinitis and asthma and has also been promising as a potential treatment for food allergy. The review summarizes significant advances from the past year including further data on the effectiveness of existing treatments, preliminary data on novel treatments, and further understanding of the mechanisms of these new therapies.

Keywords: allergic rhinitis; allergic rhinoconjunctivitis; asthma; food allergy; oral immunotherapy; sublingual immunotherapy.

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Conflict of interest statement

Conflict of Interest

Edwin H Kim is on the medical advisory board for Triangle E Technologies and Kyruus. Wesley Burks is the President of AAAAI; is currently a consultant to GLG Research, Nutricia North America, and Regeneron Pharmaceuticals; received honoraria from Levine's Children's Hospital; received payment for development of educational presentations from Mylan Specialty; and has stock/stock options with Mastcell Pharmaceuticals.

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