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Comment
. 2014 Nov 1;20(21):5346-8.
doi: 10.1158/1078-0432.CCR-14-1121. Epub 2014 Aug 18.

Matching wits with melanoma brain metastases: from biology to therapeutics

Hussein Tawbi  1
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Comment

Matching wits with melanoma brain metastases: from biology to therapeutics

Hussein Tawbi. Clin Cancer Res. .

Abstract

Melanoma brain metastases (MBM) present a significant clinical challenge. Molecular profiling of MBM is useful to identify molecular pathways, such as the PI3K pathway, that are specifically and differentially altered in MBM. Therapeutic studies should recruit patients with MBM and prospective tissue collection will lay the foundation for further advances.

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