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Comment
. 2014 Aug 18;24(16):R755-7.
doi: 10.1016/j.cub.2014.07.018.

Genetics: finding genes for schizophrenia

Jonathan Flint  1 , Marcus R Munafò  2
Affiliations
Comment

Genetics: finding genes for schizophrenia

Jonathan Flint et al. Curr Biol. .

Abstract

New studies have substantially advanced our understanding of the genetic architecture of schizophrenia, but we are far from identifying the underlying mutations. We may require new approaches to understand the biological implications of insights into the genetics of psychiatric disease.

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Comment on

  • A polygenic burden of rare disruptive mutations in schizophrenia.
    Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, O'Dushlaine C, Chambert K, Bergen SE, Kähler A, Duncan L, Stahl E, Genovese G, Fernández E, Collins MO, Komiyama NH, Choudhary JS, Magnusson PK, Banks E, Shakir K, Garimella K, Fennell T, DePristo M, Grant SG, Haggarty SJ, Gabriel S, Scolnick EM, Lander ES, Hultman CM, Sullivan PF, McCarroll SA, Sklar P. Purcell SM, et al. Nature. 2014 Feb 13;506(7487):185-90. doi: 10.1038/nature12975. Epub 2014 Jan 22. Nature. 2014. PMID: 24463508 Free PMC article.
  • Biological sunscreens tune polychromatic ultraviolet vision in mantis shrimp.
    Bok MJ, Porter ML, Place AR, Cronin TW. Bok MJ, et al. Curr Biol. 2014 Jul 21;24(14):1636-1642. doi: 10.1016/j.cub.2014.05.071. Epub 2014 Jul 3. Curr Biol. 2014. PMID: 24998530
  • Biological insights from 108 schizophrenia-associated genetic loci.
    Schizophrenia Working Group of the Psychiatric Genomics Consortium. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22. Nature. 2014. PMID: 25056061 Free PMC article.

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