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. 2014 Aug 20;9(8):e105030.
doi: 10.1371/journal.pone.0105030. eCollection 2014.

Non-occupational post-exposure prophylaxis for HIV: 10-year retrospective analysis in Seattle, Washington

Sarah J McDougal  1 , Jeremiah Alexander  2 , Shireesha Dhanireddy  1 , Robert D Harrington  1 , Joanne D Stekler  3
Affiliations

Non-occupational post-exposure prophylaxis for HIV: 10-year retrospective analysis in Seattle, Washington

Sarah J McDougal et al. PLoS One. .

Abstract

Despite treatment guidelines in place since 2005, non-occupational post-exposure HIV prophylaxis (nPEP) remains an underutilized prevention strategy. We conducted a retrospective chart review of patients presenting to a publicly-funded HIV clinic in Seattle, Washington for nPEP between 2000 and 2010 (N = 360). nPEP prescriptions were provided for 324 (90%) patients; 83% of prescription decisions were appropriate according to Centers for Disease Control and Prevention guidelines, but only 31% (N = 111/360) of patients were considered "high risk." In order to use limited resources most efficiently, public health agencies should target messaging for this high-cost intervention to individuals with high-risk HIV exposures.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

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