No evidence of HTLV-1 infection in Japanese multiple sclerosis patients in polymerase chain reaction
- PMID: 2514161
- PMCID: PMC5917914
- DOI: 10.1111/j.1349-7006.1989.tb02251.x
No evidence of HTLV-1 infection in Japanese multiple sclerosis patients in polymerase chain reaction
Abstract
To test possible association of human T cell leukemia virus type 1 (HTLV-1) with multiple sclerosis (MS), polymerase chain reaction was applied to detect HTLV-1 DNA integrated into peripheral blood mononuclear cell DNA. Nine Japanese MS patients all gave a negative result, indicating no HTLV-1 infection in these MS patients.
References
-
- ) Koprowski , H. , DeFreitas , E. C. , Harper , M.E. , Sandberg‐Wollheim , M. , Sheramata , W. A. , Robert‐Guroff , M. , Saxinger , C. W. , Feinberg , M. B. , Wong‐Staal , F. and Gallo , R. C.Multiple sclerosis and human T‐cell lympho‐tropic retroviruses . Nature , 318 , 154 – 160 ( 1985. ). - PubMed
-
- ) Hinuma , Y. , Nagata , K. , Misoka , M. , Naki , M. , Matsumoto , T. , Kinoshita , K. , Shirakawa , S. and Miyoshi , I.Adult T cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera . Proc. Natl Acad. Sci. USA , 78 , 6476 – 6480 ( 1981. ). - PMC - PubMed
-
- ) Kalyanaraman , V. S. , Sarngadharan , M. G. , Nakao , Y. , Ito , Y. , Aoki , T. and Gallo , R. C.Natural antibodies to the structural core protein (p24) of the human T cell leukemia (lymphoma) retrovirus found in sera of leukemia patients in Japan . Proc. Natl Acad. Sci. USA , 79 , 1653 – 1657 ( 1982. ). - PMC - PubMed
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