MHC-II: a mutual support system for ILCs and T cells?
- PMID: 25148019
- DOI: 10.1016/j.immuni.2014.07.006
MHC-II: a mutual support system for ILCs and T cells?
Abstract
Innate and adaptive immune cells form an ongoing partnership during an immune response. In this issue of Immunity, Oliphant et al. (2014) show that MHC class II-peptide presentation by group 2 innate lymphoid cells is needed for reciprocal regulation of both cell types, resulting in effective antihelminth immunity.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.Immunity. 2014 Aug 21;41(2):283-95. doi: 10.1016/j.immuni.2014.06.016. Epub 2014 Jul 31. Immunity. 2014. PMID: 25088770 Free PMC article.
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