Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep 15;59 Suppl 2(Suppl 2):S71-5.
doi: 10.1093/cid/ciu392.

The future of antibiotics and resistance: a tribute to a career of leadership by John Bartlett

Affiliations

The future of antibiotics and resistance: a tribute to a career of leadership by John Bartlett

Brad Spellberg et al. Clin Infect Dis. .

Abstract

The ways we have developed, used, and protected antibiotics have led, predictably, to our current crisis of rising antibiotic resistance and declining new treatments. If we want to stave off a postantibiotic era, we need to fundamentally change our approach. We need to challenge long-standing assumptions and cherished beliefs. We need to push through the reflexive resistance and excuses (eg, "that's not how we do things" and "that can't be done") that result from challenging established ways. Excuses abound. Action is needed. Ultimately, we need a coordinated national action plan to combat resistance. Herein we discuss 7 tasks and 3 common themes that cut across those tasks, which are necessary to achieve long-term success in dealing with antibiotics and resistance. These principles derive from many years of dialogue with Dr John Bartlett. The field of infectious diseases, and indeed medicine in general, has benefited immeasurably from his remarkable leadership.

Keywords: antibiotics; future; policies; resistance.

PubMed Disclaimer

References

    1. Johnson AS. Annual oration: medicine's responsibility in the propagation of poor protoplasm. N Engl J Med. 1948;238:755–8. - PubMed
    1. Chambers HF. The changing epidemiology of Staphylococcus aureus`? Emerg Infect Dis. 2001;7:178–82. - PMC - PubMed
    1. Burnet M. Natural history of infectious disease. Cambridge, England: Cambridge University Press; 1962.
    1. Finland M, Kirby WM, Chabbert YA, et al. Round table: are new antibiotics needed? Antimicrob Agents Chemother. 1965;5:1107–14. - PubMed
    1. Petersdorf RG. The doctors’ dilemma. N Engl J Med. 1978;299:628–34. - PubMed

Publication types