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Review
. 2014 Sep;28(3):403-20.
doi: 10.1016/j.idc.2014.05.004.

Antiretroviral therapy: when to start

Affiliations
Review

Antiretroviral therapy: when to start

Christopher J Sellers et al. Infect Dis Clin North Am. 2014 Sep.

Abstract

In this article, the scientific evidence and professional guidelines regarding the timing of antiretroviral therapy initiation are reviewed, with discussion of the increasingly persuasive evidence in favor of starting treatment early in the course of human immunodeficiency virus disease.

Keywords: Antiretroviral; CD4; Human immunodeficiency virus; Initiation; Start; Therapy; Timing.

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Figures

Figure 1
Figure 1
Evolution of CD4+ Count Criteria for Starting Antiretroviral Therapy in Asymptomatic Persons with Human Immunodeficiency Virus Infection, According to Different Guidelines
Figure 2
Figure 2
Years after ART initiation to achieving CD4 > 750 by CD4+ cell count stratum at ART initiation: HOPS Cohort 1996–2012 (N=1,327)

References

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    1. Panel on antiretroviral guidelines for adults and adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human services; [Accessed February 16, 2014]. Available at: http://Aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL000721.pdf. Updated 2007.
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