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. 2014 Jun 10;94(22):1744-6.

[Feasibility study of secure closure of esophageal perforation with over-the-scope clips in a canine model]

[Article in Chinese]
He Guo  1 , Xiuli Zhang  1 , Ping Tang  1 , Gang Sun  1 , Rugang Zhang  1 , Yunsheng Yang  2
Affiliations
  • PMID: 25151909

[Feasibility study of secure closure of esophageal perforation with over-the-scope clips in a canine model]

[Article in Chinese]
He Guo et al. Zhonghua Yi Xue Za Zhi. .

Abstract

Objective: To evaluate the feasibility and safety of endoscopic closure of esophageal perforation with an over-the-scope clip (OTSC) system in a surviving canine model.

Methods: Esophageal perforations (20-mm diameter) were created by an endoscopic needle-knife in 10 dogs. Then the perforations were closed by the OTSC system. And gastroscopy was performed weekly to evaluate the postoperative perforation healing.

Results: Esophageal perforations could primarily be closed with one OTSC in each experimental dog. The mean handling time was 24 (18-33) min. All animals survived without postoperative complications. The retention of OTSC was observed in all dogs at the end of 3 weeks.

Conclusion: The OTSC system can reliably close esophageal perforations without complications.

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