Monitoring residual disease in the ph-negative myeloproliferative neoplasms post-allogeneic stem cell transplantation: more mutations and more methodologies
- PMID: 25152868
- PMCID: PMC4126362
- DOI: 10.3389/fonc.2014.00212
Monitoring residual disease in the ph-negative myeloproliferative neoplasms post-allogeneic stem cell transplantation: more mutations and more methodologies
Keywords: CALR; JAK2 V617F; allogeneic stem cell transplantation; digital PCR; myeloproliferative neoplasms; next generation sequencing; residual disease.
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References
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- Steckel NK, Koldehoff M, Ditschkowski M, Beelen DW, Elmaagacli AH. Use of the activating gene mutation (Val617Phe) JAK2 as a minimal residual disease marker in patients with myelofibrosis and myeloid metaplasia after allogeneic stem cell transplantation. Transplantation (2007) 83:1518–2010.1097/01.tp.0000263393.65764.f4 - DOI - PubMed
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- Lange T, Edelmann A, Siebolts U, Krahl R, Nehring C, Jäkel N, et al. JAK2 p.V617F allele burden in myeloproliferative neoplasms one month after allogeneic stem cell transplantation significantly predicts outcome and risk of relapse. Haematologica (2013) 98:722–810.3324/haematol.2012.076901 - DOI - PMC - PubMed
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