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Review
. 2014 Sep;41(3):487-502.
doi: 10.1016/j.clp.2014.05.001. Epub 2014 Jul 22.

Acute kidney injury in the neonate

Jennifer G Jetton  1 , David J Askenazi  2
Affiliations
Review

Acute kidney injury in the neonate

Jennifer G Jetton et al. Clin Perinatol. 2014 Sep.

Abstract

Critically ill neonates are at risk for acute kidney injury (AKI). AKI has been associated with increased risk of morbidity and mortality in adult and pediatric patients, and increasing evidence suggests a similar association in the neonatal population. This article describes the current AKI definitions (including their limitations), work on novel biomarkers to define AKI, diagnosis and management strategies, long-term outcomes after AKI, and future directions for much-needed research in this important area.

Keywords: Acute kidney injury; Acute renal failure; Biomarkers; Chronic kidney disease; Critical illness; Neonate.

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