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Comparative Study
. 1989 Dec;8(12):1038-40.
doi: 10.1007/BF01975165.

Failure of mupirocin-resistant staphylococci to inactivate mupirocin

B Cookson  1
Affiliations
Comparative Study

Failure of mupirocin-resistant staphylococci to inactivate mupirocin

B Cookson. Eur J Clin Microbiol Infect Dis. 1989 Dec.

Abstract

Isolates from four UK centres, comprising four Staphylococcus aureus strains and one Staphylococcus epidermidis strain with high-level mupirocin resistance, and one strain each of Staphylococcus aureus and Staphylococcus epidermidis with low-level mupirocin resistance, were assessed for intracellular or extracellular enzymatic alteration of the antibiotic. No change was seen in a number of assays, which included comparative disk diffusion, well diffusion and high-pressure liquid chromatography. Other mechanisms of resistance need to be explored in these isolates.

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References

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