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. 2014:2014:631346.
doi: 10.1155/2014/631346. Epub 2014 Aug 6.

Charcot spine and Parkinson's disease

Philippe Loriaut  1 , Sylvie Rozenberg  2 , Patrick Boyer  3 , Benjamin Dallaudière  4 , Frederic Khiami  1 , Elhadi Sariali  1 , Hugues Pascal-Moussellard  1
Affiliations

Charcot spine and Parkinson's disease

Philippe Loriaut et al. Case Rep Orthop. 2014.

Abstract

Charcot spine is rare condition whose association with Parkinson's disease (PD) has not been reported yet. The authors reported the cases of two patients with PD who developed Charcot spine. Both patients presented with a history of back pain and bilateral radicular leg pain. They had complete clinical and radiological assessment. Lumbar spine was involved in both patients. Clinical features and response to treatment were described. In the first case, circumferential fusion and stabilization were performed on the dislocated vertebral levels. A solid and stable fusion of the spine was obtained with satisfactory clinical outcome. Surgical treatment has been recommended to the other patient. In both cases, no other neurological etiology was found to account for Charcot spine. In conclusion, Charcot spine is associated with several neurological affections but has not previously been reported in association with Parkinson's disease.

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Figures

Figure 1
Figure 1
Anteroposterior radiographs showing marked narrowing of L2-L3 disc space with some endplate destruction associated with new bone formation and a severe lateral dislocation of the L2/L3 joint (Case 1).
Figure 2
Figure 2
Preoperative plain radiograph (lateral view) showing marked narrowing of L2-L3 disc space with some endplate destruction; new bone formation is noted (Case 1).
Figure 3
Figure 3
CT scan showing a destruction of L2 vertebral body and L2-L3 disc space. The spinal canal was compromised with paravertebral hypertrophic ossifications (Case 1).
Figure 4
Figure 4
CT scan at the 5-year followup confirming bony union achievement and a solid and stable fusion of the spine (Case 1).
Figure 5
Figure 5
Lateral radiograph shows destruction of L4-L5 vertebral bodies producing multiple bony fragments (Case 2).
Figure 6
Figure 6
Anteroposterior radiograph shows leftward translation of L4 (Case 2).
Figure 7
Figure 7
Sagittal CT scan image showing bony destruction of L4 and L5 (Case 2).
See this image and copyright information in PMC

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