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Case Reports
. 2014 Jul;5(3):314-5.
doi: 10.4103/2229-5178.137787.

Role of tetracycline in recalcitrant erythema nodosum

Shaurya Rohatgi  1 , Kabbur Hanumantappa Basavaraj  1 , P K Ashwini  1 , Garehatty Rudrappa Kanthraj  1
Affiliations
Case Reports

Role of tetracycline in recalcitrant erythema nodosum

Shaurya Rohatgi et al. Indian Dermatol Online J. 2014 Jul.

Abstract

Erythema nodosum is a type of septal panniculitis. We report a case of 40 year old male of chronic and recalcitrant erythema nodosum who responded to tetracycline. The possible mechanism of action of tetracycline is analyzed. Tetracycline should be considered as a logical option in recalcitrant erythema nodosum.

Keywords: Erythema nodosum; tetracycline; treatment.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
(a) Hyperpigmented, indurated and tender nodule over the left leg. The nodule margin is seen around the biopsy site (b) Three similar nodules over the calf of left leg. Hyperpigmentation over the flexor aspect of right leg
Figure 2
Figure 2
(a) Septa in the subcutaneous tissue showing inflammatory infiltrate. The infiltrate is also extending into the lobules (H and E, ×4 scanner view) (b) High power view of a granuloma within in the septa showing lymphocytes, epitheloid cells and multinucleate giant cell (H and E, ×10) (c) Multinucleated giant cell with surrounding epitheloid cells and lymphocytes (H and E, ×40)
Figure 3
Figure 3
Residual hyperpigmentation after resolution of the nodules, posttreatment
See this image and copyright information in PMC

References

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