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. 2014 Sep;11(9):895-8.
doi: 10.1038/nmeth.3076.

Improved reproducibility by assuring confidence in measurements in biomedical research

Anne L Plant  1 , Laurie E Locascio  2 , Willie E May  3 , Patrick D Gallagher  4
Affiliations

Improved reproducibility by assuring confidence in measurements in biomedical research

Anne L Plant et al. Nat Methods. 2014 Sep.

Abstract

‘Irreproducibility’ is symptomatic of a broader challenge in measurement in biomedical research. From the US National Institute of Standards and Technology (NIST) perspective of rigorous metrology, reproducibility is only one aspect of establishing confidence in measurements. Appropriate controls, reference materials, statistics and informatics are required for a robust measurement process. Research is required to establish these tools for biological measurements, which will lead to greater confidence in research results.

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