Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
- PMID: 25168246
- PMCID: PMC4158092
- DOI: 10.1186/1475-2875-13-336
Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?
Abstract
A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.
Comment in
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Finding connections in the unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: a fact in the Atlantic Forest.Malar J. 2014 Aug 28;13:337. doi: 10.1186/1475-2875-13-337. Malar J. 2014. PMID: 25168319 Free PMC article.
Comment on
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Detection of Plasmodium falciparum and Plasmodium vivax subclinical infection in non-endemic region: implications for blood transfusion and malaria epidemiology.Malar J. 2014 Jun 6;13:224. doi: 10.1186/1475-2875-13-224. Malar J. 2014. PMID: 24906577 Free PMC article.
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