Novel evidence on hepatitis C virus-associated glomerular disease
- PMID: 25168497
- DOI: 10.1038/ki.2014.181
Novel evidence on hepatitis C virus-associated glomerular disease
Abstract
A large spectrum of renal pathology is associated with hepatitis C virus (HCV). According to novel evidence, occult HCV infection (HCV-RNA in peripheral blood mononuclear cells or in serum after ultracentrifugation) could be involved in the pathogenesis of glomerular nephropathy among patients negative for conventional markers of HCV. Additional studies with appropriate size and technology are in progress to confirm the relationship between occult HCV and glomerular disease, which has multiple implications from the clinical standpoint.
Comment on
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High prevalence of occult hepatitis C virus infection in patients with primary and secondary glomerular nephropathies.Kidney Int. 2014 Sep;86(3):619-24. doi: 10.1038/ki.2014.68. Epub 2014 Mar 19. Kidney Int. 2014. PMID: 24646855
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