Acute lead arsenate poisoning
- PMID: 2517192
- DOI: 10.1111/j.1445-5994.1989.tb00349.x
Acute lead arsenate poisoning
Abstract
Three cases of acute lead arsenate poisoning which occurred in South Australia during a 12 month interval are described. The case reports demonstrate a number of features of the characteristic clinical syndrome which may follow ingestion of lead arsenate. The recommended management is immediate gastric lavage and subsequent chelation therapy with calcium EDTA and dimercaprol. Early gastric lavage may prevent significant lead absorption. However, arsenic acid (produced in the stomach when lead arsenate reacts with hydrochloric acid) is relatively water soluble and prompt gastric lavage is unlikely to prevent extensive arsenic absorption. It remains controversial as to whether chelation with dimercaprol prevents arsenical neuropathy.
Comment in
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Acute lead arsenate poisoning.Aust N Z J Med. 1990 Oct;20(5):750-1. doi: 10.1111/j.1445-5994.1990.tb00413.x. Aust N Z J Med. 1990. PMID: 2126731 No abstract available.
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