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. 2015 Feb;212(2):218.e1-9.
doi: 10.1016/j.ajog.2014.08.019. Epub 2014 Aug 27.

Maternal morbidity in patients with morbidly adherent placenta treated with and without a standardized multidisciplinary approach

Alireza A Shamshirsaz  1 , Karin A Fox  2 , Bahram Salmanian  2 , Concepcion R Diaz-Arrastia  3 , Wesley Lee  2 , B Wycke Baker  4 , Jerasimos Ballas  2 , Qian Chen  2 , Teelkien R Van Veen  2 , Pouya Javadian  2 , Haleh Sangi-Haghpeykar  2 , Nicholas Zacharias  2 , Stephen Welty  5 , Christopher I Cassady  6 , Amirhossein Moaddab  2 , Edwina J Popek  7 , Shiu-ki Rocky Hui  7 , Jun Teruya  7 , Venkata Bandi  8 , Michael Coburn  9 , Thomas Cunningham  10 , Stephanie R Martin  2 , Michael A Belfort  2
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Maternal morbidity in patients with morbidly adherent placenta treated with and without a standardized multidisciplinary approach

Alireza A Shamshirsaz et al. Am J Obstet Gynecol. 2015 Feb.

Abstract

Objective: The purpose of this study was to test the hypothesis that a standardized multidisciplinary treatment approach in patients with morbidly adherent placenta, which includes accreta, increta, and percreta, is associated with less maternal morbidity than when such an approach is not used (nonmultidisciplinary approach).

Study design: A retrospective cohort study was conducted with patients from 3 tertiary care hospitals from July 2000 to September 2013. Patients with histologically confirmed placenta accreta, increta, and percreta were included in this study. A formal program that used a standardized multidisciplinary management approach was introduced in 2011. Before 2011, patients were treated on a case-by-case basis by individual physicians without a specific protocol (nonmultidisciplinary group). Estimated blood loss, transfusion of packed red blood cells, intraoperative complications (eg, vascular, bladder, ureteral, and bowel injury), neonatal outcome, and maternal postoperative length of hospital stay were compared between the 2 groups.

Results: Of 90 patients with placenta accreta, 57 women (63%) were in the multidisciplinary group, and 33 women (37%) were in the nonmultidisciplinary group. The multidisciplinary group had more cases with percreta (P = .008) but experienced less estimated blood loss (P = .025), with a trend to fewer blood transfusions (P = .06), and were less likely to be delivered emergently (P = .001) compared with the nonmultidisciplinary group. Despite an approach of indicated preterm delivery at 34-35 weeks of gestation, neonatal outcomes were similar between the 2 groups.

Conclusion: The institution of a standardized approach for patients with morbidly adherent placentation by a specific multidisciplinary team was associated with improved maternal outcomes, particularly in cases with more aggressive placental invasion (increta or percreta), compared with a historic nonmultidisciplinary approach. Our standardized approach was associated with fewer emergency deliveries.

Keywords: invasive placenta; maternal complication; placenta accreta; placenta increta; placenta percreta; standard treatment.

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