Hi-TEC reprogramming for organ regeneration
- PMID: 25174818
- DOI: 10.1038/ncb3032
Hi-TEC reprogramming for organ regeneration
Abstract
The induction of cell reprogramming by transcription factors into alternative cell fates opens new avenues for regenerative medicine. Thymic epithelial cells that were obtained from fibroblasts by Foxn1 overexpression support the formation of an ectopic thymus following transplantation.
Comment on
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An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts.Nat Cell Biol. 2014 Sep;16(9):902-8. doi: 10.1038/ncb3023. Epub 2014 Aug 24. Nat Cell Biol. 2014. PMID: 25150981 Free PMC article.
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