A helminth-mediated viral awakening
- PMID: 25174993
- DOI: 10.1016/j.it.2014.08.004
A helminth-mediated viral awakening
Abstract
Co-infections may have unpredictable consequences for the health of a host beyond the sum of the individual infections. Two recent papers in Science provide mechanistic insights into how acute helminth infections alter the outcome of Herpesvirus and Norovirus infections by triggering changes in the local cytokine environment.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
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Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter.Science. 2014 Aug 1;345(6196):573-7. doi: 10.1126/science.1254517. Epub 2014 Jun 26. Science. 2014. PMID: 24968940 Free PMC article.
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Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.Science. 2014 Aug 1;345(6196):578-82. doi: 10.1126/science.1256942. Epub 2014 Jul 17. Science. 2014. PMID: 25082704 Free PMC article.
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