Sparing surgery with the use of TiNi-based endografts in larynx cancer patients

Abstract

Background and objectives: Purpose of this study was to improve a technique of sparing surgery in patients with laryngeal cancer by using TiNi-based endografts and to achieve well functional and oncological results after laryngectomy.

Methods: Totally 120 patients with laryngeal cancer were observed (T2-3 N0-1 M0 ). We have developed a method of laryngeal reconstruction using TiNi-based endografts. All endografts show the superelastic behavior recovering the shape. All patients have undergone different types of sparing surgeries with simultaneous replacement with endografts.

Results: Voice function was completely saved in 112 cases and partially in 8 ones. Respiratory function was fully restored in 106 patients. The protective function of the larynx was achieved in 116 patients.

Conclusion: The technique allowed to achieve well oncological (the 5-year and overall recurrence-free survival rates of all 120 patients were 83% and 76%, respectively) and functional (larynx function was saved in 93% of cases) outcomes after extensive and subtotal resections in patients with locally distributed larynx cancer.

Keywords: TiNi-based endograft; larynx cancer; larynx reconstruction; prefabricated flap; sparing surgery.