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. 2014 Sep;7(3):229-31.
doi: 10.3342/ceo.2014.7.3.229. Epub 2014 Aug 1.

Nasal deformity due to tuberculous chondritis

Affiliations

Nasal deformity due to tuberculous chondritis

Soo-Youn Moon et al. Clin Exp Otorhinolaryngol. 2014 Sep.

Abstract

Tuberculosis (TB) is a common disease worldwide. However, nasal TB is quite rare, and the diagnosis of nasal TB requires a high index of suspicion. The most common symptoms of this unusual presentation are nasal obstruction and nasal discharge. We present a case of nasal TB with involvement of the hard palate presenting with a chronically progressive nasal deformity and ulceration of the hard palate. A biopsy confirmed the diagnosis, and medication for TB was started and the lesions resolved. When a patient presents with chronic ulcerative lesions that do not respond to antibiotic treatment, TB should be included in the differential diagnosis. Biopsy of the lesion can aid in the confirmation of the diagnosis.

Keywords: Chondritis; Deformity; Nose; Tuberculosis.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Initial physical examination. The patient presented with a nasal deformity with inflammation (A, B) and a chronic ulcerative lesion of the hard palate (C, arrow).
Fig. 2
Fig. 2
Computed tomography findings. Perforation of the nasal septum of cartilaginous portion and defect of external nose.
Fig. 3
Fig. 3
Histopathology of the nasal tissue. (A) Collections of epithelioid histiocytes forming granulomas and multinucleated giant cells against a necrotic background (H&E, ×100). (B) A few acid-fast bacilli were observed (Ziehl-Neelsen, ×1,000).
Fig. 4
Fig. 4
Follow-up physical examination. Following one year of treatment, the inflammation of the nasal deformity (A) and the chronic ulcerative lesion of the hard palate (B, arrow) both improved.

References

    1. Pust RE. Tuberculosis in the 1990's: resurgence, regimens, and resources. South Med J. 1992 Jun;85(6):584–593. - PubMed
    1. Kim YM, Kim AY, Park YH, Kim DH, Rha KS. Eight cases of nasal tuberculosis. Otolaryngol Head Neck Surg. 2007 Sep;137(3):500–504. - PubMed
    1. Morgagni GB. On the seats and causes of diseases as investigated by anatomy. Venice. 1761;1:50–55.
    1. Butt AA. Nasal tuberculosis in the 20th century. Am J Med Sci. 1997 Jun;313(6):332–335. - PubMed
    1. Harries AD, Dye C. Tuberculosis. Ann Trop Med Parasitol. 2006 Jul-Sep;100(5-6):415–431. - PubMed