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Comparative Study
. 1989;47(5):290-5.

[The transmembrane diffusion of trinitrine and isosorbide dinitrate. Study of artificial membranes]

[Article in French]
A M Guyot-Hermann, J Ringard, J L Parier, C Lefebvre, C Barthelemy
  • PMID: 2517772
Comparative Study

[The transmembrane diffusion of trinitrine and isosorbide dinitrate. Study of artificial membranes]

[Article in French]
A M Guyot-Hermann et al. Ann Pharm Fr. 1989.

Abstract

Nitroglycerin pharmacodynamic efficiency is 3 to 4 times higher than isosorbide dinitrate efficiency. Data of this study on physiological and artificial membranes point the greater nitroglycerin transmembrane diffusion, which is discussed as a possible relevant explanation.

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