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Case Reports
. 2014 Sep;72(7):380-2.

Hepatocellular carcinoma after danazol treatment for hereditary angio-oedema

A E M Berkel  1 , D E Bouman, M R Schaafsma, C Verhoef, J M Klaase
Affiliations
  • PMID: 25178775
Free article
Case Reports

Hepatocellular carcinoma after danazol treatment for hereditary angio-oedema

A E M Berkel et al. Neth J Med. 2014 Sep.
Free article

Abstract

Hereditary angio-oedema is characterised by recurrent episodes of laryngeal, intra-abdominal, facial or peripheral oedema. Danazol can be used as prophylaxis for recurrent attacks. Hepatotoxicity is a recognised adverse effect of danazol. We report an exceptional case of a danazol-induced hepatocellular carcinoma in a 75-year-old patient with hereditary angio-oedema.

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