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Case Reports
. 2014 Jul;5(3):410-4.
doi: 10.4103/0976-237X.137976.

Idiopathic thrombocytopenic purpura

Affiliations
Case Reports

Idiopathic thrombocytopenic purpura

L Kayal et al. Contemp Clin Dent. 2014 Jul.

Abstract

Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. The major causes of accelerated platelet consumption include immune thrombocytopenia, decreased bone marrow production, and increased splenic sequestration. The clinical presentation may be acute with severe bleeding, or insidious with slow development with mild or no symptoms. The initial laboratory tests useful at the first visit to predict future diagnosis were erythrocyte count, leukocyte count, anti-glycoprotein IIb/IIIa antibodies, reticulated platelets, plasma thrombopoietin level. Treatment should be restricted to those patients with moderate or severe thrombocytopenia who are bleeding or at risk of bleeding. We present a case report on ITP with clinical presentation, diagnosis and management.

Keywords: Hematoma; idiopathic thrombocytopenic purpura; petechiae; platelets.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Petechial spots over the neck
Figure 2
Figure 2
Petechial spots over the right arm
Figure 3
Figure 3
Inflamed, bleeding gingiva
Figure 4
Figure 4
Hematoma formation in lower anterior gingiva
Figure 5
Figure 5
Hematoma formation lingually anteriorly
Figure 6
Figure 6
Resolved hematoma anteriorly
Figure 7
Figure 7
Resolved hematoma lingually

References

    1. Cines DB, Bussel JB. How I treat idiopathic thrombocytopenic purpura (ITP) Blood. 2005;106:2244–51. - PubMed
    1. Cines DB, McMillan R. Management of adult idiopathic thrombocytopenic purpura. Annu Rev Med. 2005;56:425–42. - PubMed
    1. Coopamah MD, Garvey MB, Freedman J, Semple JW. Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update. Transfus Med Rev. 2003;17:69–80. - PubMed
    1. Schwartz RS. Immune thrombocytopenic purpura - From agony to agonist. N Engl J Med. 2007;357:2299–301. - PubMed
    1. Semple JW, Freedman J. Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia. Blood. 1991;78:2619–25. - PubMed

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