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. 2014 Nov;16(11):346.
doi: 10.1007/s11936-014-0346-x.

Cardiovascular disease associated with the human immunodeficiency virus: an update

Thomas S Metkus Jr  1 , Todd T Brown, Wendy S Post
Affiliations

Cardiovascular disease associated with the human immunodeficiency virus: an update

Thomas S Metkus Jr et al. Curr Treat Options Cardiovasc Med. 2014 Nov.

Abstract

With the advent of increasingly available antiretroviral therapy (ART), the life expectancy of HIV-infected persons is increasing. As they age, HIV-infected persons have increased propensity to typical diseases of aging including cardiovascular disease and accelerated atherosclerosis. The pathogenesis of HIV-associated atherosclerosis is complex and involves a state of chronic inflammation, exposure to traditional risk factors, and metabolic side effects of ART. Treatment of HIV-associated atherosclerosis should include special attention to drug-drug interactions and is best accomplished by a multidisciplinary team experienced in the care of HIV-infected persons.

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