Review
[Cephalosporins: bacterial resistance measured by penicillin-binding proteins]
[Article in
Spanish]
- PMID: 2519470
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Review
[Cephalosporins: bacterial resistance measured by penicillin-binding proteins]
[Article in
Spanish]
Rev Med Chil.
1989 Sep.
Abstract
Antibacterial potency of cephalosporins depends on inhibition (acylation) of one or more penicillin-binding proteins (PBP). Recently, reduced affinity of PBP for cephalosporins and other B-lactam agents has been found in some cases. Mechanism for these changes in affinity are analyzed in this review.
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