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Comment
. 2014 Sep;20(9):989-90.
doi: 10.1038/nm.3685.

Inhibiting Janus kinases to treat alopecia areata

Sherrie J Divito  1 , Thomas S Kupper  1
Affiliations
Comment

Inhibiting Janus kinases to treat alopecia areata

Sherrie J Divito et al. Nat Med. 2014 Sep.

Abstract

Alopecia areata is an immune-mediated, nonscarring form of hair loss. A new study using human clinical samples and a mouse model demonstrates that CD8αβ⁺NKG2D⁺ T effector memory cells mediate alopecia areata in part through Janus kinase (JAK) signaling and that alopecia areata might be treated with JAK inhibitors.

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