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Comparative Study
. 2014 Aug;18(8):958-60.
doi: 10.5588/ijtld.13.0328.

Xpert(®) MTB/RIF assay for tuberculosis diagnosis: evaluation in an Indian setting

V P Myneedu  1 , D Behera  1 , A K Verma  1 , M Bhalla  1 , N Singh  1 , J Arora  1 , R Singhal  1 , M Mathur  1 , P Lal  1 , R Sarin  1
Affiliations
Comparative Study

Xpert(®) MTB/RIF assay for tuberculosis diagnosis: evaluation in an Indian setting

V P Myneedu et al. Int J Tuberc Lung Dis. 2014 Aug.

Abstract

The present study was conducted to evaluate the performance of the Xpert(®) MTB/RIF assay and compare Xpert results with solid and MGIT 960 liquid culture system. A total of 134 patients who had failed the Category I or II regimen were recruited for evaluation. Xpert correctly identified all Mycobacterium tuberculosis isolates. The sensitivity and specificity of the Xpert assay for the detection of rifampicin resistance was respectively 98.2% and 97.0% when compared with MGIT 960 results.

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