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. 2014 Dec;66(12):3521-3.
doi: 10.1002/art.38870.

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus

Elena López-Isac  1 , Lara Bossini-Castillo, Sandra G Guerra, Christopher Denton, Carmen Fonseca, Shervin Assassi, Xiaodong Zhou, Maureen D Mayes, Carmen Pilar Simeón, Norberto Ortego-Centeno, Iván Castellví, Patricia Carreira; Spanish Scleroderma Group; Olga Gorlova, Lorenzo Beretta, Alessandro Santaniello, Claudio Lunardi, Roger Hesselstrand, Annika Nordin, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H W Distler, Alexandre E Voskuyl, Jeska de Vries-Bouwstra, Bobby P Koeleman, Ariane Herrick, Jane Worthington, Timothy R D J Radstake, Javier Martin
Affiliations

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus

Elena López-Isac et al. Arthritis Rheumatol. 2014 Dec.
No abstract available

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References

    1. Martin JE, Bossini-Castillo L, Martin J. Unraveling the genetic component of systemic sclerosis. Hum Genet. 2012;131:1023–1037. - PubMed
    1. Radstake TR, Gorlova O, Rueda B, et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet. 2010;42:426–429. - PMC - PubMed
    1. Vignali DA, Kuchroo VK. IL-12 family cytokines: immunological playmakers. Nat Immunol. 2012;13:722–728. - PMC - PubMed
    1. Mayes MD, Bossini-Castillo L, Gorlova O, et al. Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet. 2014;94:47–61. - PMC - PubMed
    1. Bossini-Castillo L, Martin JE, Broen J, et al. A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet. 2012;21:926–933. - PMC - PubMed

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